It’s very possible. Running the instance over and over again in regular mode, you learn attacks from the bosses, what mobs to skip over, etc. Only difference is you have mutation effects to move away/dodge/heal/stack gem resist on, and the mobs/bosses hit harder the higher you go up in the mutations.
same reason random have such a hard time in dynasty
gen and laz spoiled the crap out of players.
(dynasty having a super broken last boss though is a different issue something broke like a patch ago. no sound queues randomized or missing pedestals are causing issues)
After all the struggle in non-mutated runs with a lot of respawns and wipes I was expecting worse, tbh But today I ran my first M2 Tempest with random guys from global chat and we did it in 39 minutes, 2 respawns (1 by accident), and no real problems. Sure, our GS was way higher than required but still. Looking forward to higher M’s.
P.S. One possible “issue” is normal enemies’ kill count. We had it at like 89-90/120. Looking at screenshots here, I see others run it the same way Maybe a bit too much? On the other hand, with 15 minutes left we could wipe all the map out and still have plenty on the clock.
Im a tank and all off my team was dead, boss have 25% Hp and i soloed it, just dodging and lifesteahl (5% on spear and 5% bonering) s&s and it was nice in mutation 4. I was not skilled in dex just from the spear, just believe in your selfe